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Nolvadex Dosage
Adaugat pe 08/08/2019 18:13:23 de freemexy

For patients with breast cancer, the recommended daily dose is 20-40
mg. Dosages greater than 20 mg per day should be given in divided doses
(morning and evening).

In three single agent adjuvant studies in women, one 10 mg NOLVADEX
tablet was administered two (ECOG and NATO) or three (Toronto) times a
day for two years. In the NSABP B-14 adjuvant study in women with
node-negative breast cancer, one 10 mg NOLVADEX tablet was given twice a
day for at least 5 years. Results of the B-14 study suggest that
continuation of therapy beyond five years does not provide additional
benefit (see CLINICAL PHARMACOLOGY). In the EBCTCG 1995 overview, the
reduction in recurrence and mortality was greater in those studies that
used tamoxifen for about 5 years than in those that used tamoxifen for a
shorter period of therapy. There was no indication that doses greater
than 20 mg per day were more effective. Current data from clinical
trials support 5 years of adjuvant NOLVADEX therapy for patients with
breast cancer.Nolvadex dosage

The recommended dose is NOLVADEX 20 mg daily for 5 years. There are no
data to support the use of NOLVADEX other than for 5 years (See CLINICAL
PHARMACOLOGY-Clinical Studies – Reduction in Breast Cancer Incidence in
High Risk Women).

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